Aztreonam Impurity 84 CAS CATO-C4X-152284
| CAS No. | CATO-C4X-152284 |
| Molecular Formula | C19H26N8O12S3 |
| Molecular Weight | 654.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 654.65 g/mol gives Aztreonam Impurity 84 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Aztreonam Impurity 84 (CAS CATO-C4X-152284, C19H26N8O12S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Aztreonam Impurity 84 (C19H26N8O12S3) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H26N8O12S3 |
| Molecular Weight | 654.65 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 3 |
Related Aztreonam Standards
- Aztreonam Impurity 3 (CAS CATO-C4X-15223)
- Aztreonam Impurity 58 (CAS CATO-C4X-152258)
- Aztreonam impurity 94 (CAS CATO-C4X-152294)
- Aztreonam Impurity 108 (CAS CATO-C4X-1522108)
- Aztreonam impurity 118 (CAS CATO-C4X-1522118)
- Aztreonam Impurity 2 (CAS CATO-C4X-15222)
- Aztreonam Impurity 20 (CAS CATO-C4X-152220)
- Aztreonam Impurity 23 (CAS CATO-C4X-152223)
Recommended Standards
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- Tranilast Impurity 10 (CAS CATO-C4X-252910)
- Almotriptan Impurity 16 (CAS CATO-C4X-153816)
- Propofol impurity 62 (CAS 110007-31-3)
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