Formoterol Impurity 60 CAS CATO-C4X-152560
| CAS No. | CATO-C4X-152560 |
| Molecular Formula | C17H18BrNO3 |
| Molecular Weight | 364.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Formoterol Impurity 60 (CAS CATO-C4X-152560, C17H18BrNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Formoterol Impurity 60 (C17H18BrNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H18BrNO3 |
| Molecular Weight | 364.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Formoterol Standards
- Formoterol Impurity 58 (CAS 725719-13-1)
- Formoterol EP Impurity C (CAS 1795135-61-3)
- Formoterol EP Impurity D (CAS 1795133-96-8)
- Formoterol EP Impurity E (CAS 1616967-26-0)
- Formoterol Impurity 89 (CAS CATO-C4X-152589)
- Formoterol impurity 125 (CAS CATO-C4X-1525125)
- Formoterol impurity 130 (CAS CATO-C4X-1525130)
- Formoterol impurity 139 (CAS CATO-C4X-1525139)
Recommended Standards
- N-[(3,4-Dichlorophenyl)methyl]-6,7-dimethoxyquinazolin-4-amine (CAS 477859-87-3)
- 2-((5-Bromothiophen-2-yl)sulfonyl)-N-(furan-2-ylmethyl)acetamide (CAS 1020971-01-0)
- N-(2,4-dichlorobenzyl)-6,7-dimethoxyquinazolin-4-amine (CAS 477855-23-5)
- N-(3-Methoxyphenyl)-4,6-bis(trifluoromethyl)pyridine-2-carboxamide (CAS 1092345-27-1)
- Articaine Impurity14 (CAS CATO-C4X-191214)
- Amikacin impurity 28 (CAS 197909-66-3)
- Vitamin B6 (Pyridoxine) Impurity 40 HCl (CAS 875-26-3)
- Ondansetron Impurity 11 (CAS CATO-C4X-139411)
- 5-(3-(Trifluoromethyl)phenyl)pyrimidin-2-ol (CAS 75175-37-0)
- Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers] (CAS 6809-52-5)
- 1-(2-Chlorophenyl)-2-(4-hydroxypiperidin-1-yl)ethan-1-one (CAS 1338691-62-5)
- Di-tert-butyl Peroxide (CAS 110-05-4)
- Sodium 2,3-dioxoindoline-5-sulfonate dihydrate (CAS 207399-16-4)
- Immunstimulating Peptide, human (CAS 94773-24-7)
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