Bosentan Impurity 20 CAS CATO-C4X-156420

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-156420
Molecular FormulaC9H8N4O3
Molecular Weight220.18 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bosentan Impurity 20 CAS CATO-C4X-156420 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 220.18 g/mol gives Bosentan Impurity 20 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Bosentan Impurity 20 (CAS CATO-C4X-156420) is a certified pharmaceutical impurity reference standard with the molecular formula C9H8N4O3 and a molecular weight of 220.18 g/mol.

The molecular framework of Bosentan Impurity 20 (C9H8N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Bosentan Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H8N4O3
Molecular Weight220.18 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms4

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