Parecoxib Impurity 77 CAS CATO-C4X-159177
| CAS No. | CATO-C4X-159177 |
| Molecular Formula | C19H17N3O5S |
| Molecular Weight | 399.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Parecoxib Impurity 77 (CAS CATO-C4X-159177, C19H17N3O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Parecoxib Impurity 77 (C19H17N3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Parecoxib Impurity 77 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17N3O5S |
| Molecular Weight | 399.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Parecoxib Standards
- Parecoxib Impurity 26 (CAS CATO-C4X-159126)
- Parecoxib Impurity 42 (CAS CATO-C4X-159142)
- Parecoxib Impurity 43 (CAS 1373038-59-5)
- Parecoxib Impurity 53 (CAS CATO-C4X-159153)
- Parecoxib Impurity 54 (CAS CATO-C4X-159154)
- Parecoxib Impurity 55 (CAS CATO-C4X-159155)
- Parecoxib Impurity 56 (CAS CATO-C4X-159156)
- Parecoxib Impurity 57 (CAS CATO-C4X-159157)
Recommended Standards
- Sunitinib impurity 69 (CAS CATO-C4X-133369)
- Letermovir impurity 113 (CAS CATO-C4X-2915113)
- Moxifloxacin Impurity 62 (CAS CATO-C4X-107462)
- 2-[(2R)-2-hydroxy-3-[2,3,5,6-tetradeuterio-4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione (CAS 1329838-35-8)
- Apixaban Impurity 9 (CAS 503614-91-3)
- Asenapine Impurity C95 (CAS 129385-60-0)
- Rivaroxaban EP Impurity A (CAS 865479-71-6)
- 5-Cyclopropoxy-2-isopropoxyisonicotinic acid (CAS 1243365-34-5)
- 4-Nitrotoluene-2,3,5,6-D4 (CAS 1276197-16-0)
- 5-chloro-N-methylpyrimidin-2-amine (CAS 45715-16-0)
- 4-Bromo-5-(trifluoromethyl)thiophene-2-carboxylic acid (CAS 1034188-24-3)
- 5-(piperidin-3-yl)-4-(propan-2-yl)-4H-1,2,4-triazole-3-thiol hydrochloride (CAS 1269152-36-4)
- 2-(3,5-Dichlorophenyl)-2-(methylamino)acetic acid (CAS 1218501-54-2)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
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