Minocycline Impurity 60 CAS CATO-C4X-169960
| CAS No. | CATO-C4X-169960 |
| Molecular Formula | C22H22N2O8 |
| Molecular Weight | 442.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Minocycline Impurity 60.
CATO supplies Minocycline Impurity 60 (CAS CATO-C4X-169960), a pharmacopoeial impurity reference standard (molecular formula C22H22N2O8, MW 442.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H22N2O8, Minocycline Impurity 60 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 442.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22N2O8 |
| Molecular Weight | 442.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Minocycline Standards
- Minocycline impurity 55 (CAS CATO-C4X-169955)
- Minocycline Impurity 58 (CAS CATO-C4X-169958)
- Minocycline Impurity 63 (CAS CATO-C4X-169963)
- Minocycline EP Impurity C (CAS 4708-96-7)
- Minocycline Impurity 53 (CAS CATO-C4X-169953)
- Minocycline Impurity 69 (CAS CATO-C4X-169969)
- Minocycline Impurity 68 (CAS CATO-C4X-169968)
- Minocycline EP Impurity I (CAS 5874-95-3)
Recommended Standards
- Doxycycline EP Impurity B (CAS CATO-C4X-19312)
- Azilsartan Impurity 13 (CAS 1403474-78-1)
- Sodium Cromoglicate Impurity 25 (CAS 40786-63-8)
- Azilsartan Impurity 105 (CAS 147403-35-8)
- Cloxacillin Impurity 32 (CAS CATO-C4X-159732)
- Afoxolaner impurity 4 (CAS CATO-C4X-31374)
- Mometasone Impurity 39 (CAS 2408910-08-5)
- 5-Methyl-3-phenyl-1-tosyl-1H-1,2,4-triazole (CAS 647376-09-8)
- N-(3,4-dichlorobenzyl)-N-ethylglycine (CAS 1184050-14-3)
- Etomidate Impurity 35 (CAS CATO-C4X-188435)
- 1-Methyl-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid (CAS 178316-79-5)
- Ixazomib Impurity 24 (CAS CATO-C4X-126724)
- 6-Bromo-4-chloro-8-fluoro-2-methoxyquinazoline (CAS 2275753-56-3)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com