Indobufen Impurity 26 CAS CATO-C4X-179226
| CAS No. | CATO-C4X-179226 |
| Molecular Formula | C18H16ClNO3 |
| Molecular Weight | 329.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Indobufen Impurity 26 (CAS CATO-C4X-179226), a pharmacopoeial impurity reference standard (molecular formula C18H16ClNO3, MW 329.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Indobufen Impurity 26 (C18H16ClNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Indobufen Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16ClNO3 |
| Molecular Weight | 329.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Indobufen Standards
- Indobufen Impurity 23 (CAS CATO-C4X-179223)
- Indobufen Impurity 11 (CAS 36691-02-8)
- Indobufen Impurity N2 (CAS 36691-07-3)
- Indobufen Impurity 54 (CAS CATO-C4X-179254)
- Indobufen Impurity 75 (CAS CATO-C4X-179275)
- Indobufen Impurity 53 (CAS CATO-C4X-179253)
- Indobufen Impurity 93 (CAS CATO-C4X-179293)
- Indobufen Impurity 41 (CAS CATO-C4X-179241)
Recommended Standards
- Indacaterol Impurity 80 (CAS 869868-63-3)
- Lornoxicam Impurity 35 (CAS CATO-C4X-201635)
- Metoclopramide Impurity 111 (CAS CATO-C4X-1415111)
- Lornoxicam Impurity 40 (CAS CATO-C4X-201640)
- Topiramate Impurity 10 (CAS 66900-93-4)
- Urapidil Impurity 114 (CAS CATO-C4X-1924114)
- Fluocinolone Acetonide Impurity 35 (CAS CATO-C4X-238135)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com