(Z)-Ceftizoxime Impurity 19 CAS CATO-C4X-179319
| CAS No. | CATO-C4X-179319 |
| Molecular Formula | C13H15N5O6S2 |
| Molecular Weight | 401.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
(Z)-Ceftizoxime Impurity 19 (C13H15N5O6S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies (Z)-Ceftizoxime Impurity 19 (CAS CATO-C4X-179319), a pharmacopoeial impurity reference standard (molecular formula C13H15N5O6S2, MW 401.42 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H15N5O6S2 |
| Molecular Weight | 401.42 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Z Standards
- (Z)-Ceftizoxime Impurity 18 (CAS CATO-C4X-179318)
- (E)-Ceftizoxime open ring Impurity 1 (CAS CATO-C4X-179321)
- (Z)-Ceftizoxime Open Ring Impurity 2 (CAS CATO-C4X-179330)
- (Z)-Ceftizoxime Impurity 34 (CAS CATO-C4X-179334)
- (E)-Ceftizoxime Impurity 35 (CAS CATO-C4X-179335)
- (E)-Ceftizoxime Impurity 4 (CAS CATO-C4X-17934)
- (E)-Ceftizoxime Impurity 61 (CAS CATO-C4X-179361)
- Ceftizoxime Impurity 76 (CAS CATO-C4X-179376)
Recommended Standards
- Cinacalcet Impurity 89 (CAS CATO-C4X-105989)
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- (2R,3R,4S,5R)-2-(2-(Benzyloxy)-6-(ethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 515138-94-0)
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