(E)-Ceftizoxime Impurity 66 CAS CATO-C4X-179366
| CAS No. | CATO-C4X-179366 |
| Molecular Formula | C13H13N5O5S2 |
| Molecular Weight | 383.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, (E)-Ceftizoxime Impurity 66 (CAS CATO-C4X-179366, C13H13N5O5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
(E)-Ceftizoxime Impurity 66 (C13H13N5O5S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures (E)-Ceftizoxime Impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13N5O5S2 |
| Molecular Weight | 383.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related E Standards
- (E)-Ceftizoxime Impurity 1 (CAS 68403-31-6)
- (Z)-Ceftizoxime Impurity 17 (CAS CATO-C4X-179317)
- (Z)-Ceftizoxime Impurity 2 (CAS 2630907-20-7)
- (E)-Ceftizoxime Impurity 20 (CAS CATO-C4X-179320)
- Ceftizoxime (CAS 68401-81-0)
- (Z)-Ceftizoxime Impurity 59 (CAS CATO-C4X-179359)
- Ceftizoxime RC 4 (CAS 929101-89-3)
- Ceftizoxime Ring-opening decarboxylation S-oxide 2 (CAS CATO-C4X-179340)
Recommended Standards
- Perampanel Impurity 11 (CAS CATO-C4X-243011)
- (Z/E)-Ceftizoxime Impurity 50 (CAS 770660-21-4)
- Gadodiamide Impurity 3 (CAS CATO-C4X-31433)
- Fmoc-Glu(OMe)-OH (CAS 145038-50-2)
- Atracurium Impurity 41 (CAS CATO-C4X-185041)
- Levamisole EP Impurity C (CAS 32190-33-3)
- Tenofovir Alafenamide Impurity 26 (CAS CATO-C4X-179726)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com