Pranoprofen Impurity 48 CAS CATO-C4X-181148
| CAS No. | CATO-C4X-181148 |
| Molecular Formula | C30H24Cl2N2O4 |
| Molecular Weight | 547.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Pranoprofen Impurity 48 (CAS CATO-C4X-181148), a pharmacopoeial impurity reference standard (molecular formula C30H24Cl2N2O4, MW 547.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Pranoprofen Impurity 48 (C30H24Cl2N2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C30H24Cl2N2O4 |
| Molecular Weight | 547.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Pranoprofen Standards
- Pranoprofen Impurity 74 (CAS CATO-C4X-181174)
- Pranoprofen Impurity 78 (CAS CATO-C4X-181178)
- Pranoprofen Impurity 27 (CAS CATO-C4X-181127)
- Pranoprofen Impurity 39 (CAS CATO-C4X-181139)
- Pranoprofen Impurity 56 (CAS CATO-C4X-181156)
- Pranoprofen Impurity 4 (CAS CATO-C4X-18114)
- Pranoprofen Impurity 72 (CAS CATO-C4X-181172)
- Pranoprofen Impurity 73 (CAS CATO-C4X-181173)
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