Nintedanib Impurity 112 CAS CATO-C4X-1814112
| CAS No. | CATO-C4X-1814112 |
| Molecular Formula | C15H17NO5 |
| Molecular Weight | 291.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Nintedanib Impurity 112 (CAS CATO-C4X-1814112) is a certified pharmaceutical impurity reference standard with the molecular formula C15H17NO5 and a molecular weight of 291.30 g/mol.
The molecular framework of Nintedanib Impurity 112 (C15H17NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Nintedanib Impurity 112 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H17NO5 |
| Molecular Weight | 291.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Nintedanib Standards
- Nintedanib Impurity 167 (CAS CATO-C4X-1814167)
- Nintedanib Impurity 126 (CAS CATO-C4X-1814126)
- Nintedanib Impurity 130 (CAS CATO-C4X-1814130)
- Nintedanib Impurity 131 (CAS CATO-C4X-1814131)
- Nintedanib Impurity 159 (CAS CATO-C4X-1814159)
- Nintedanib Impurity 6 (CAS 1139453-98-7)
- Nintedanib Impurity 124 (CAS CATO-C4X-1814124)
- Nintedanib Nintedanib Impurity 88 (CAS CATO-C4X-181488)
Recommended Standards
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- Nisoldipine Impurity 2 (CAS CATO-C4X-18652)
- Trimethoprim EP Impurity E (CAS 60729-91-1)
- Nisoldipine Impurity 6 (CAS 61312-59-2)
- Olanzapine Impurity 39 (CAS 1319722-10-5)
- Rizatriptan EP Impurity I Methanesulfonic acid salt (CAS 144034-84-4 (free base)）)
- Clenbuterol impurity 17 (CAS CATO-C4X-199317)
- (S)-2-amino-N-(4-iodophenyl)-3-methylbutanamide hydrochloride (CAS 1822234-81-0)
- Methyl 3-(piperidin-1-ylmethyl)benzoate (CAS 73278-90-7)
- 2-(3-Amino-4-methyl-1h-pyrazol-1-yl)-N-propylacetamide (CAS 1342748-79-1)
- 2,4-Dibromo-3,5-dimethylaniline (CAS 125756-94-7)
- Ethyl 5-amino-4-methyl-1H-pyrazole-3-carboxylate (CAS 1357795-98-2)
- 2-Methyl-2-[2-(trifluoromethyl)phenyl]-propanoic acid (CAS 1220019-86-2)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com