Cefcapene Impurity 49 CAS CATO-C4X-182449
| CAS No. | CATO-C4X-182449 |
| Molecular Formula | C8H11ClO3 |
| Molecular Weight | 190.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cefcapene Impurity 49 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Cefcapene Impurity 49 (CAS CATO-C4X-182449, C8H11ClO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Cefcapene Impurity 49 (C8H11ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 190.62 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11ClO3 |
| Molecular Weight | 190.62 g/mol |
| Purity | ≥90% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
Related Cefcapene Standards
- Cefcapene Impurity 50 (CAS CATO-C4X-182450)
- Cefcapene Pivoxil Impurity 12 (CAS 133217-74-0)
- Cefcapene Impurity 22 (CAS 118109-49-2)
- Cefcapene Impurity 40 (CAS CATO-C4X-182440)
- Cefcapene Impurity 44 (CAS CATO-C4X-182444)
- Cefcapene Impurity 32 (CAS 1450899-66-7)
- Cefcapene Impurity 33 (CAS CATO-C4X-182433)
- Cefcapene Impurity 86 (CAS 2165460-37-5)
Recommended Standards
- 1,3-BENZODIOXOLE-5-CARBONYL CHLORIDE 25054-53-9 2H-1,3-BENZODIOXOLE-5-CARBONYL CHLORIDE 3,4-(METHYLENEDIOXY)BENZOYL CHLORIDE AS00011 BENZO[1,3]DIOXOLE-5-CARBONYL CHLORIDE BUTTPARK 154\04-36 Benzo[d][1,3]dioxole-5-carbonyl chloride OTAVA-BB 1375532 PIPERONYLOYL CHLORIDE (CAS 25054-53-9)
- O-(3-Fluorophenyl) carbonochloridothioate (CAS 42908-74-7)
- 2-Chloro-3,3'-bipyridine (CAS 101001-94-9)
- 4-Fluorophenyl Chlorothionoformate (CAS 42908-73-6)
- Cyclophosphamide Impurity 3 DiHCl (CAS CATO-C4X-23063)
- Etoposide impurity 22 (CAS 153975-25-8)
- Carfilzomib Impurity N2 (CAS 1396006-45-3)
- (R)-3-(((Benzyloxy)carbonyl)amino)pentanoicacid (CAS 1263078-28-9)
- 1-((4-Bromo-3-(trifluoromethyl)phenyl)sulfonyl)-4-methylpiperazine (CAS 486422-42-8)
- 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(dimethylamino)-1,2-diphenylethyl]amino]-3-cyclobutene-1,2-dione (CAS 1263205-97-5)
- (E)-3-(furan-2-yl)-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-one (CAS 339018-12-1)
- 5-Boc-1-oxa-5-azaspiro[2.4]heptane (CAS 301226-25-5)
- 2,4-Di-tert-butyl-6-(phenylamino)phenol (CAS 94876-25-2)
- Tirzepatide (CAS 2023788-19-2)
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