Amphotericin B Impurity 8 CAS CATO-C4X-18448
| CAS No. | CATO-C4X-18448 |
| Molecular Formula | C48H73NO18 |
| Molecular Weight | 952.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Amphotericin B Impurity 8 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Amphotericin B Impurity 8 (CAS CATO-C4X-18448) is a certified pharmaceutical impurity reference standard with the molecular formula C48H73NO18 and a molecular weight of 952.09 g/mol.
Amphotericin B Impurity 8 (C48H73NO18) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amphotericin B Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C48H73NO18 |
| Molecular Weight | 952.09 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Amphotericin Standards
- Amphotericin B ChP Impurity E (CAS CATO-C4X-184414)
- Amphotericin B Impurity 28 (CAS CATO-C4X-184428)
- Amphotericin B Ethyl Ester (CAS 55298-62-9)
- Amphotericin B Impurity 27 (CAS CATO-C4X-184427)
- Amphotericin B EP Impurity C (CAS CATO-C4X-18444)
- Amphotericin Impurity 9 (CAS CATO-C4X-18449)
- Amphotericin Methyl Ester-d3 (CAS CATO-CCAD303860)
- Amphotericin B Impurity 21 (CAS CATO-C4X-184421)
Recommended Standards
- N-Formyl Amphotericin B (CAS 1314099-20-1)
- Ethylenebistetrabromophthalimide (CAS 32588-76-4)
- Bromo(5-acetyl-2-thienyl)[2-(di-1-adamantylphosphino)-3,6-dimethoxy-2', 4',6'-tri-i-propyl-1,1'-biphenyl]palladium(II) (CAS 1805783-53-2)
- Cis-5,8,11,14 Trieicosatetraenoin (CAS 23314-57-0)
- Artemisinin Impurity 2 (CAS 1453465-55-8)
- Parecoxib Impurity 34 (CAS CATO-C4X-159134)
- Regadenoson Impurity 22 (CAS 2004-07-1)
- Ethyl 2-methyl-3-oxohexanoate (CAS 29304-40-3)
- (Pyridin-2-yl)methyl 6-(benzylcarbamoyl)-4-(trifluoromethyl)pyridine-2-carboxylate (CAS 1209118-44-4)
- 4-(Cycloheptylamino)-4-oxobutanoic acid (CAS 545349-11-9)
- 2-Bromo-3-cyclopropoxy-5-fluoropyridine (CAS 1243469-70-6)
- 6-(N-Methylphenylsulfonamido)hexanoic acid (CAS 46948-72-5)
- Pyridoxine 3,4-dipalmitate (CAS 992-42-7)
- Fibrinogen Related Peptide (CAS 80755-86-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com