Daclatasvir Impurity 33 CAS CATO-C4X-184833
| CAS No. | CATO-C4X-184833 |
| Molecular Formula | C16H11Br3O2 |
| Molecular Weight | 474.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Daclatasvir Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Daclatasvir Impurity 33 (CAS CATO-C4X-184833), a pharmacopoeial impurity reference standard (molecular formula C16H11Br3O2, MW 474.97 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Daclatasvir Impurity 33 (C16H11Br3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 474.97 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H11Br3O2 |
| Molecular Weight | 474.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Daclatasvir Standards
- Daclatasvir Impurity 23 (CAS CATO-C4X-184823)
- Daclatasvir Impurity 7 (CAS 1447744-93-5)
- Daclatasvir Impurity 15 (CAS CATO-C4X-184815)
- Daclatasvir Impurity 14 (CAS CATO-C4X-184814)
- Daclatasvir Impurity 16 (CAS CATO-C4X-184816)
- Daclatasvir EP Impurity H (CAS 1007882-27-0)
- Daclatasvir Impurity 9 (CAS CATO-C4X-18489)
- Daclatasvir impurity 38 (CAS CATO-C4X-184838)
Recommended Standards
- N'-[(1Z)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene]-2,3-dimethylquinoxaline-6-carbohydrazide (CAS 860787-43-5)
- 1,1,1,3,5,5,5-Heptamethyl-3-octadecyltrisiloxane (CAS 167160-55-6)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(1H-indazol-6-yl)acetamide (CAS 476485-80-0)
- 2-Methoxyethyl 2-(2-chlorobenzylidene)-7-methyl-3-oxo-5-(thiophen-2-yl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 617698-62-1)
- Nalmefene Impurity 25 (CAS CATO-C4X-126825)
- Mitomycin Impurity 8 Trifluoroacetate (cis-1-Hydroxy-2,7-diamino Mitosene Trifluoroacetate) (CAS 98462-75-0 (free base))
- Ambroxol Impurity 80 (CAS CATO-C4X-108580)
- (4-Chloro-3-nitro-1h-pyrazol-1-yl)methanol (CAS 957023-24-4)
- 6,7-difluoro-3-methyl-chromen-4-one (CAS 2847139-12-0)
- 2-[3-(3-Methylbutoxy)phenyl]ethanamine (CAS 1178489-28-5)
- Bromhexine D-Glucose Derivative (CAS CATO-C4X-106021)
- Ethyl 6-(dimethylamino)nicotinate (CAS 1216268-65-3)
- 5-Bromo-2-chloro-4-fluorophenyl acetate (CAS 148254-36-8)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
Why CATO?
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