Arotinolol Impurity 35 CAS CATO-C4X-185435
| CAS No. | CATO-C4X-185435 |
| Molecular Formula | C8H8BrNO2S |
| Molecular Weight | 262.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Arotinolol Impurity 35 (CAS CATO-C4X-185435, C8H8BrNO2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Arotinolol Impurity 35 (C8H8BrNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 262.12 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8BrNO2S |
| Molecular Weight | 262.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Arotinolol Standards
- Arotinolol impurity 28 (CAS CATO-C4X-185428)
- Arotinolol Impurity 42 (CAS 57797-77-0)
- Arotinolol Impurity 36 (CAS 52561-15-6)
- Arotinolol Impurity 76 (CAS CATO-C4X-185476)
- Arotinolol impurity 25 (CAS 96991-65-0)
- Arotinolol Impurity 11 (CAS 68257-90-9)
- Arotinolol impurity 26 (CAS 96991-51-4)
- Arotinolol Impurity 67 (CAS CATO-C4X-185467)
Recommended Standards
- 3,5-dichloro-2-hydroxy-n-isobutylbenZamide (CAS 100127-25-1)
- 6-Bromo-4-imino-2,3-dihydrobenzo[b][1,4]oxathiine 4-oxide (CAS 2219376-14-2)
- 2,4-Dichloro-N-ethyl-N-(2-hydroxyethyl)benzamide (CAS 1011574-09-6)
- 6-Bromo-2-methyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide (CAS 2027538-58-3)
- Hydantoin Impurity 28 (CAS CATO-C4X-214628)
- Tirofiban Impurity 107 HCl (CAS CATO-C4X-1254107)
- Isavuconazole Impurity 118 (CAS CATO-C4X-1236118)
- N-{2-[bis(propan-2-yl)amino]ethyl}piperidine-4-carboxamide dihydrochloride (CAS 1172699-87-4)
- Methyl 3-cyclohexylpropanoate (CAS 20681-51-0)
- 3-Formyl-4-(3-oxomorpholino)benzonitrile (CAS 1260825-80-6)
- 5-Nitrobenzo[d][1,3]dioxole-2-thione (CAS 1051374-82-3)
- 2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine (CAS 1026-05-7)
- Metamizole Impurity 15 (CAS 23197-23-1)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
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