pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-GIn-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 CAS CATO-C4X-186237

Purity >95%In StockPharmaceutical Standards
CAS No.CATO-C4X-186237
Molecular FormulaC128H164N36O26
Molecular Weight2622.90 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-GIn-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 CAS CATO-C4X-186237 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-GIn-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2.

CATO supplies pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-GIn-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 (CAS CATO-C4X-186237), a certified reference material (molecular formula C128H164N36O26, MW 2622.90 g/mol) for analytical method development and quality control.

The molecular framework of pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-GIn-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 (C128H164N36O26) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-GIn-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC128H164N36O26
Molecular Weight2622.90 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)65.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms36

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