Methylene blue /Methylthioninium Chloride Impurity 28 CAS CATO-C4X-189628
| CAS No. | CATO-C4X-189628 |
| Molecular Formula | C16H18N4OS |
| Molecular Weight | 314.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C16H18N4OS, Methylene blue /Methylthioninium Chloride Impurity 28 contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 314.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Methylene blue /Methylthioninium Chloride Impurity 28 (CAS CATO-C4X-189628, C16H18N4OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18N4OS |
| Molecular Weight | 314.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methylene Standards
- Methylene blue /Methylthioninium Chloride Impurity 21 (CAS CATO-C4X-189621)
- Methylene blue /Methylthioninium Chloride Impurity 35 (CAS CATO-C4X-189635)
- 2,2'-MEthylene-bis(n-(2-[((5-[(dimethylamino)methyl]-2-furanyl)thio)ethyl]-n'-methyl)-2-nitro-1,1'-ethenediamine) (CAS 1241891-40-6)
- 4-Methylene-3,5-diphenyl-5-(1,2,2-trimethylhydrazinyl)-4,5-dihydroisoxazole (CAS 62033-10-7)
- 3-Methylene-5-(4-(morpholinosulfonyl)phenyl)dihydrofuran-2(3H)-one (CAS 77547-03-6)
- Methylene blue /Methylthioninium Chloride Impurity 33 (CAS CATO-C4X-189633)
- Methylene blue /Methylthioninium Chloride Impurity 36 (CAS CATO-C4X-189636)
- Methylene blue Impurity 15 (CAS CATO-C4X-189615)
Recommended Standards
- N-Butyl-5-((quinolin-8-yloxy)methyl)-1,3,4-thiadiazol-2-amine (CAS 90208-26-7)
- 3,4-Difluoro-4'-(trans-4-propylcyclohexyl)biphenyl (CAS 85312-59-0)
- N-(2-(2-(o-Tolyl)thiazolo[3,2-b][1,2,4]triazol-6-yl)ethyl)propionamide (CAS 941950-59-0)
- Diazinon-d10 (CAS 100155-47-3)
- Perospirone Impurity 53 (CAS CATO-C4X-245853)
- Teneligliptin impurity 57 (CAS CATO-C4X-176057)
- Darifenacin Impurity 4 (CAS CATO-C4X-16054)
- 2-(Benzylthio)ethan-1-amine hydrochloride (CAS 22572-33-4)
- Posaconazole Impurity 66 (CAS 2423024-31-9)
- 4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrole-3-carboxylic acid (CAS 1152964-22-1)
- H-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Cys-OH (CAS CATO-CPTD788982)
- 2-Bromomethyl-4-methyl-5-pentafluoroethylpyridine (CAS 1246466-59-0)
- tert-Butyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)acetate (CAS 769968-17-4)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
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