Dequalinium Impurity 8 CAS CATO-C4X-19368
| CAS No. | CATO-C4X-19368 |
| Molecular Formula | C20H30IN2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dequalinium Impurity 8 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Dequalinium Impurity 8 (CAS CATO-C4X-19368, C20H30IN2Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dequalinium Impurity 8 (C20H30IN2Cl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dequalinium Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H30IN2 Cl |
| Molecular Weight | 460.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Dequalinium Standards
- Dequalinium 2*Chloride x*Hydrate (CAS 1255077-34-9)
- Dequalinium Impurity 15 (CAS 15821-13-3)
- Dequalinium Impurity 4 (CAS 16355-92-3)
- Dequalinium EP Impurity C trichloride (CAS 171980-50-0)
- Dequalinium Chloride EP Impurity B chloride (CAS 171980-52-2)
- Dequalinium Impurity 7 (CAS 19056-26-9)
- Dequalinium iodide (CAS 2019-42-3)
- Dequalinium impurity 18 (CAS 2377370-96-0)
Recommended Standards
- Dienogest Impurity 20 (CAS 34686-78-9)
- Cipepofol Impurity 3 (CAS 1637741-59-3)
- N-Nitroso Diphenhydramine Impurity 11 (CAS CATO-C4X-142411)
- Ac-N-Me-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) (CAS 160806-26-8)
- 6-Chloroimidazo[1,2-a]pyridine-5-carboxylic acid (CAS 1414864-10-0)
- 6-Hydroxybenzofuran-2(3H)-one (CAS 2688-49-5)
- 7-(Difluoromethyl)-1-methyl-7,8-dihydroquinoline-2,5(1H,6H)-dione (CAS 1706437-89-9)
- 3-Methylbenzoyl isocyanate (CAS 5893-29-8)
- 2-(4-Boc-Aminopiperidino)pyridine (CAS 252578-12-4)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com