3’’-HABA Kanamycin A xSulfate ( Amikacin EP Impurity C xSulfate) CAS CATO-C4X-19777
| CAS No. | CATO-C4X-19777 |
| Molecular Formula | C22H43N5O13 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, 3’’-HABA Kanamycin A xSulfate ( Amikacin EP Impurity C xSulfate) (CAS CATO-C4X-19777, C22H43N5O13·xH2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, 3’’-HABA Kanamycin A xSulfate ( Amikacin EP Impurity C xSulfate) (C22H43N5O13·xH2O4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 683.68 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H43N5O13 ·xH2O4S |
| Molecular Weight | 683.68 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related HABA Standards
Recommended Standards
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- Mirabegron Impurity 13 (CAS 1684452-85-4)
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- 4-(3-Bromophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 259750-15-7)
- 2-Cyano-3-(trifluoromethyl)phenylboronic acid (CAS 1198181-40-6)
- 3-{2-[2-(2-(diphenylamino)-3-{2-[1-(3-sulfonatopropyl)naphtho[1,2-d][1,3]thiazol-1-ium-2-yl]ethenyl}-2-cyclopenten-1-ylidene)ethylidene]naphtho[1,2-d][1,3]thiazol-1- yl}-1-propanesulfonate (CAS 28645-14-9)
- Trimethyl-1-propanaminium Iodide (CAS 1652-63-7)
- Finerenone Impurity 131 (CAS CATO-C4X-2880131)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
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