Bumetanide Impurity 129 CAS CATO-C4X-1986129

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1986129
Molecular FormulaC18H22N2O5S
Molecular Weight378.44 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bumetanide Impurity 129 CAS CATO-C4X-1986129 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bumetanide Impurity 129.

Bumetanide Impurity 129 (CAS CATO-C4X-1986129) is a certified pharmaceutical impurity reference standard with the molecular formula C18H22N2O5S and a molecular weight of 378.44 g/mol.

Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Bumetanide Impurity 129 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Bumetanide Impurity 129 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H22N2O5S
Molecular Weight378.44 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms2
Sulfur Atoms1

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