Bromfenac Impurity 27 CAS CATO-C4X-200227

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-200227
Molecular FormulaC16H11BrClNO
Molecular Weight348.62 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bromfenac Impurity 27 CAS CATO-C4X-200227 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 348.62 g/mol gives Bromfenac Impurity 27 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Bromfenac Impurity 27 (CAS CATO-C4X-200227) is a certified pharmaceutical impurity reference standard with the molecular formula C16H11BrClNO and a molecular weight of 348.62 g/mol.

Structurally, Bromfenac Impurity 27 (C16H11BrClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 348.62 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Bromfenac Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H11BrClNO
Molecular Weight348.62 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl/Br-containing
Nitrogen Atoms1

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