Brivaracetam Impurity 141 CAS CATO-C4X-2007141

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2007141
Molecular FormulaC14H25BrO4
Molecular Weight337.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Brivaracetam Impurity 141 CAS CATO-C4X-2007141 chemical structure

Description

The occurrence of Brivaracetam Impurity 141 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Brivaracetam Impurity 141 (CAS CATO-C4X-2007141), a pharmacopoeial impurity reference standard (molecular formula C14H25BrO4, MW 337.25 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Brivaracetam Impurity 141 (C14H25BrO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H25BrO4
Molecular Weight337.25 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityHygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
Halogen ContentBr-containing

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