Brivaracetam Impurity 182 CAS CATO-C4X-2007182
| CAS No. | CATO-C4X-2007182 |
| Molecular Formula | C11H20N2O2 |
| Molecular Weight | 212.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Brivaracetam Impurity 182 (C11H20N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Brivaracetam Impurity 182 (CAS CATO-C4X-2007182, C11H20N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Brivaracetam Impurity 182 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H20N2O2 |
| Molecular Weight | 212.29 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 2 |
Related Brivaracetam Standards
- Brivaracetam (CAS 357336-20-0)
- Brivaracetam impurity 104 (CAS 357334-83-9)
- Brivaracetam Impurity 131 (CAS CATO-C4X-2007131)
- Brivaracetam Impurity 144 (CAS CATO-C4X-2007144)
- Brivaracetam Impurity 2 (CAS 357336-19-7)
- Brivaracetam Impurity 3 (CAS 357336-99-3)
- Brivaracetam Impurity 4 (CAS 357337-00-9)
- Brivaracetam Impurity 74 (CAS CATO-C4X-200774)
Recommended Standards
- Irbesartan Impurity 48 (CAS 253269-07-7)
- Difenidol Impurity 10 (CAS 5180-33-6)
- Irbesartan Impurity 46 (CAS CATO-C4X-166646)
- Guaiazulene impurity 11 (CAS 24687-70-5)
- Diclofenac Impurity 25 (CAS CATO-C4X-105125)
- Cefuroxime Impurity 79 (CAS CATO-C4X-124579)
- Clodronate Disodium EP Impurity A Pyridinium Salt (CAS 134757-52-1 (free acid))
- N-[1-((S)-2-Amino-3-methyl-butyryl)-piperidin-2-ylmethyl]-N-methyl-acetamide (CAS 1354028-03-7)
- 1-(3-(Methylthio)phenyl)ethan-1-ol (CAS 58114-13-9)
- Sodium 2,3-dioxoindoline-5-sulfonate dihydrate (CAS 207399-16-4)
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