Brivaracetam Impurity 189 CAS CATO-C4X-2007189
| CAS No. | CATO-C4X-2007189 |
| Molecular Formula | C11H22N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Brivaracetam Impurity 189 (C11H22N2O3C4H4O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Brivaracetam Impurity 189 (CAS CATO-C4X-2007189, C11H22N2O3C4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H22N2O3 C4H4O4 |
| Molecular Weight | 346.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Brivaracetam Standards
- Brivaracetam impurity 112 (CAS 10414-69-4)
- Brivaracetam Impurity 56 (CAS 104652-77-9)
- Brivaracetam Impurity 36 (CAS 10547-88-3)
- Brivaracetam Impurity 64 (CAS 112106-16-8)
- Brivaracetam Impurity 23 (CAS 112459-79-7)
- Brivaracetam impurity 103 (CAS 114148-86-6)
- Brivaracetam-d7 (Mixture of Diastereomers) (CAS 1202896-51-2)
- Brivaracetam impurity 98 (CAS 1262340-22-6)
Recommended Standards
- Cinacalcet Impurity 19 (CAS 22038-83-1)
- Carteolol Impurity 25 (CAS 5220-49-5)
- Levonorgestrel Impurity 29 (CAS CATO-C4X-167729)
- 5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (CAS 7135-02-6)
- (1-(tert-butoxycarbonyl)-6-(4-(tert-butoxycarbonyl)piperazine-1-carbonyl)-1H-indol-2-yl)boronic acid (CAS 913388-59-7)
- 6-Chloro-2-ethyl-3-methylpyridine (CAS 1330756-36-9)
- 2-Bromo-N-((S)-1-phenylethyl)butanamide (CAS 1344962-49-7)
- 3-Ethyl-6-methyl-1,3,5-triazine-2,4(1H,3H)-dione (CAS 69032-73-1)
- (4-Amino-2-chloro-phenyl)-carbamic acid tert-butyl ester (CAS 342882-96-6)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
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