Brivaracetam Impurity 49 CAS CATO-C4X-200749
| CAS No. | CATO-C4X-200749 |
| Molecular Formula | C13H22N2O3 |
| Molecular Weight | 254.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Brivaracetam Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Brivaracetam Impurity 49 (CAS CATO-C4X-200749), a pharmacopoeial impurity reference standard (molecular formula C13H22N2O3, MW 254.33 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Brivaracetam Impurity 49 (C13H22N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H22N2O3 |
| Molecular Weight | 254.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Brivaracetam Standards
- Brivaracetam Impurity 148 (CAS CATO-C4X-2007148)
- Brivaracetam Impurity 152 (CAS CATO-C4X-2007152)
- Brivaracetam Impurity 124 (CAS CATO-C4X-2007124)
- Brivaracetam Impurity 186 (CAS CATO-C4X-2007186)
- Brivaracetam Impurity 149 (CAS CATO-C4X-2007149)
- Brivaracetam Impurity 33 (CAS CATO-C4X-200733)
- Brivaracetam Impurity 181 (CAS CATO-C4X-2007181)
- Brivaracetam Impurity 167 (CAS CATO-C4X-2007167)
Recommended Standards
- Piperazine Impurity 6 (CAS 62755-64-0)
- Butalbital Impurity 9 (CAS CATO-C4X-19839)
- 1,1＇-Binaphthyl (CAS 604-53-5)
- Prilocaine Impurity 11 (CAS CATO-C4X-193411)
- Nicergoline Impurity 18 (CAS CATO-C4X-208518)
- Cabazitaxel Impurity 33 (CAS CATO-C4X-111533)
- Hesperidin Impurity 3 (CAS CATO-C4X-33273)
- 3-(2-Cyano-4,5-dimethoxyphenyl)-1-cyclohexylthiourea (CAS 343375-03-1)
- N-(4-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-methylbenzamide (CAS 868370-98-3)
- 2-Chloro-N-(2-chlorobenzyl)-N-ethylacetamide (CAS 1183985-03-6)
- (S)-2-Amino-4-(3-methylphenyl)butanoic acid (CAS 1260589-05-6)
- N-(2-Amino-5-hydroxy-6-methylpyrimidin-4-yl)-3-methylbenzamide (CAS 61581-41-7)
- 1-Isopropyl-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 2137783-72-1)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
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