Artemisinin Impurity 1 CAS CATO-C4X-20121
| CAS No. | CATO-C4X-20121 |
| Molecular Formula | C14H19NO |
| Molecular Weight | 217.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Artemisinin Impurity 1 (CAS CATO-C4X-20121, C14H19NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H19NO, Artemisinin Impurity 1 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 217.31 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Artemisinin Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19NO |
| Molecular Weight | 217.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Artemisinin Standards
- Artemisinin Impurity 10 (CAS 2989438-72-2)
- Artemisinin Impurity 3 (CAS CATO-C4X-20123)
- Artemisinin Impurity 5 (CAS 1093625-96-7)
- Artemisinin Impurity 6 (CAS CATO-C4X-20126)
- Artemisinin Impurity 17 (CAS CATO-C4X-201217)
- Artemisinin Impurity 9 (CAS CATO-C4X-20129)
- 9-epi-Artemisinin (CAS 113472-97-2)
- Artemisinin (CAS 63968-64-9)
Recommended Standards
- Prilocaine Impurity 24 (CAS CATO-C4X-193424)
- Bilastine Impurity 73 (CAS 874895-87-1)
- Lobeline impurity 20 (CAS 101113-68-2)
- Pentoxyverine Impurity 15 (CAS CATO-C4X-227015)
- Norepinephrine Impurity 64 (CAS CATO-C4X-151464)
- Netupitant Impurity 9 HCl (CAS 290297-24-4)
- Ipratropium Bromide EP Impurity F (CAS 60018-35-1)
- 2-Amino-5-(trifluoromethyl)thieno[2,3-d]pyrimidin-4(1H)-one (CAS 1423165-37-0)
- 8-Oxabicyclo[3.2.1]Octan-6-amine (CAS 2167942-09-6)
- 4-[(2-Methylphenoxy)methyl]benzoic acid (CAS 149288-30-2)
- 7-(4-Chloro-3-nitrophenyl)-2-methylpyrazolo[1,5-a]pyrimidine (CAS 478249-07-9)
- (3'-Hydroxy-5'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)(pyrrolidin-3-yl)methanone (CAS 1261985-14-1)
- 1-(4-Chlorophenyl)-2-(ethylsulfonyl)ethanone (CAS 139268-89-6)
- Semaglutide Impurity 123 (CAS 71997-93-8)
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