Trifluridine Impurity 10 CAS CATO-C4X-205610
| CAS No. | CATO-C4X-205610 |
| Molecular Formula | C38H30Cl4O11 |
| Molecular Weight | 804.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 804.45 g/mol gives Trifluridine Impurity 10 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Trifluridine Impurity 10 (CAS CATO-C4X-205610, C38H30Cl4O11) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Trifluridine Impurity 10 (C38H30Cl4O11) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Trifluridine Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C38H30Cl4O11 |
| Molecular Weight | 804.45 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Trifluridine Standards
- Trifluridine Impurity 6 (CAS 129664- 48-8)
- Trifluridine Impurity 7 (CAS CATO-C4X-20567)
- Trifluridine (CAS 70-00-8)
- Trifluridine Impurity 3 (CAS 7057-42-3)
- Trifluridine Impurity 5 (CAS CATO-C4X-20565)
- Trifluridine Related Compound A (CAS 14599-46-3)
- Trifluridine Impurity 4 (CAS 4449-28-9)
- Trifluridine/tipiracil (TAS-102) Impurity D (CAS 91447-90-4)
Recommended Standards
- 1-amino-4-[4-[[4-chloro-6-(2-sulfoanilino)-1,3,5-triazin-2-yl]amino]-3-sulfo-anilino]-9,10-dioxo-anthracene-2-sulfonic acid 2-Anthracenesulfonic acid, 1-amino-4-[[4-[[4-chloro-6-[(2-sulfophenyl)amino]-1,3,5-triazin-2-yl]amino]-3-sulfophenyl]amino]-9,10-dihydro-9,10-dioxo- 84166-13-2 Cibacron blue 3GA (CAS 84166-13-2)
- (11bR)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-4-hydroxydinaphtho[2,1-d:1 inverted exclamation marka,2 inverted exclamation marka-f]-1,3,2-dioxaphosphepin 4-oxide (R)-3,3 inverted exclamation marka-Bis[3,5-bis(trifluoromethyl)phenyl]-1,1 inverted exclamation marka-bi-2-naphthol cyclic monophosphate (R)-3,3 inverted exclamation marka-Bis[3,5-bis(trifluoromethyl)phenyl]-1,1 inverted exclamation marka-binaphthyl-2,2 inverted exclamation marka-diyl hydrogenphosphate 791616-62-1 (CAS 791616-62-1)
- 4,4'-(Ethane-1,2-diylbis(azaneylylidene))bis(1,1,1,7,7,7-hexafluoro-2,6-bis(trifluoromethyl)heptane-2,6-diol) (CAS 824414-01-9)
- 5,5'-Diisopropyl-3,3'-dimethyl-8,8'-bis(((3-(trifluoromethyl)phenyl)imino)methyl)-[2,2'-binaphthalene]-1,1',6,6',7,7'-hexaol (CAS 6945-74-0)
- Efinaconazole Impurity 7 (CAS CATO-C4X-12437)
- Siponimod Impurity 34 (CAS 2768181-14-0)
- Arbidol Impurity 30 (CAS CATO-C4X-112930)
- 1-{[4-(methoxymethyl)phenyl]sulfanyl}-N,N-dimethylformamide (CAS 1354951-42-0)
- 8-Chloroisoquinoline 2-oxide (CAS 70810-27-4)
- Acetylcholine Bromide (CAS 66-23-9)
- (S)-4-Amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)-N-tritylpropanamido)-4-oxobutanoic acid (CAS 500872-21-9)
- 5-Amino-1-(5-hydroxypentyl)pyridin-2(1h)-one (CAS 1249854-66-7)
- (17 β)-17-[(1-Oxo-10-undecen-1-yl)oxy]-androsta-1,4,6-trien-3-one (CAS 1800195-99-6)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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