Ruxolitinib Impurity 44 CAS CATO-C4X-205844
| CAS No. | CATO-C4X-205844 |
| Molecular Formula | C29H22O14 |
| Molecular Weight | 594.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ruxolitinib Impurity 44 (CAS CATO-C4X-205844), a pharmacopoeial impurity reference standard (molecular formula C29H22O14, MW 594.48 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Ruxolitinib Impurity 44 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 594.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ruxolitinib Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H22O14 |
| Molecular Weight | 594.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 202 (CAS 3016399-18-8)
- Ruxolitinib Impurity 82 (CAS CATO-C4X-205882)
- Ruxolitinib Impurity 43 (CAS CATO-C4X-205843)
- Ruxolitinib Impurity 26 (CAS CATO-C4X-205826)
- Ruxolitinib Impurity 97 (CAS CATO-C4X-205897)
- Ruxolitinib Impurity 81 (CAS CATO-C4X-205881)
- Ruxolitinib Impurity 18 (CAS CATO-C4X-205818)
- Ruxolitinib Impurity 28 (CAS CATO-C4X-205828)
Recommended Standards
- Alectinib Impurity 72 (CAS CATO-C4X-283672)
- (1R,2R,4S)-1,3,3-Trimethylbicyclo[2.2.1]heptan-2-yl acetate (CAS 99341-77-2)
- Alectinib Impurity 71 (CAS CATO-C4X-283671)
- 1-3-5-Tri-O-benzoyl-2-O-(trifluoromethanesulfonyl)-α-D-ribofuranose (CAS 97614-41-0)
- Mirabegron Impurity 139 (CAS 1330277-46-7)
- Olodaterol Impurity 15 (CAS CATO-C4X-194315)
- Axitinib Impurity 43 (CAS 1959572-97-4)
- (11bS)-N,N,2,6-Tetramethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 185449-86-9)
- 5-(Benzofuran-2-yl)-1H-indazole (CAS 885272-61-7)
- 4-[(3-hydroxypropyl)sulfanyl]benzoic acid (CAS 254910-61-7)
- Pentyl 4-hydroxy-3,5-dimethoxybenzoate (CAS 223907-48-0)
- (R)-3-Phenyl-2-(2-phenylacetamido)propanoic acid (CAS 54076-39-0)
- N2-(2-Amino-6-chloropyrimidin-4-yl)-6-chloro-N4,N4-diethylpyrimidine-2,4-diamine (CAS 881939-91-9)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com