Papaverine Impurity 44 CAS CATO-C4X-206744
| CAS No. | CATO-C4X-206744 |
| Molecular Formula | C19H21NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 363.84 g/mol gives Papaverine Impurity 44 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Papaverine Impurity 44 (CAS CATO-C4X-206744, C19H21NO4HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Papaverine Impurity 44 (C19H21NO4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21NO4 HCl |
| Molecular Weight | 363.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Papaverine Standards
- Papaverine-d3 Hydrochloride (CAS 113718-66-4)
- Papaverine Impurity 37 (CAS 1207386-32-0)
- Papaverine Hydrochloride - Impurity E (CAS 13074-31-2)
- Papaverine EP Impurity F (CAS 139-76-4)
- Papaverine Impurity 35 (CAS 16637-56-2)
- Papaverine Impurity 14 Hcl (CAS 18694-10-5（free base）)
- Papaverine Impurity 17 (CAS 18783-43-2)
- Papaverine Impurity 2 (CAS 18813-60-0)
Recommended Standards
- Salbutamol Impurity 76 HCI (CAS 870076-73-6（free base）)
- Mirabegron Impurity 93 (CAS CATO-C4X-103293)
- Plerixafor Impurity 10 (CAS 80413-59-8)
- tert-Butyl 3-((4-chloro-5-methylpyrimidin-2-yl)amino)piperidine-1-carboxylate (CAS 1261233-17-3)
- Edoxaban Impurity 83 (CAS CATO-C4X-106383)
- 5-Methanesulfonyl-4-piperidin-4-yl-pyrimidine dihydrochloride (CAS 1361115-94-7)
- (2Z)-2-(Phenylmethylidene)-2,3,4,9-tetrahydro-1H-carbazol-1-one (CAS 1164562-06-4)
- Dimethyl 4-bromo-5-cyanophthalate (CAS 2616552-11-3)
- (E)-[2-(4-Fluorophenoxy)-1-(4-methoxyphenyl)ethylidene](methoxy)amine (CAS 338400-75-2)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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