Dihydralazine Impurity 5 CAS CATO-C4X-20785
| CAS No. | CATO-C4X-20785 |
| Molecular Formula | C16H8Cl2N4O |
| Molecular Weight | 343.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 343.17 g/mol gives Dihydralazine Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Dihydralazine Impurity 5 (CAS CATO-C4X-20785, C16H8Cl2N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dihydralazine Impurity 5 (C16H8Cl2N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 343.17 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2N4O |
| Molecular Weight | 343.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dihydralazine Standards
- Dihydralazine Impurity 6 (CAS CATO-C4X-20786)
- Dihydralazine EP Impurity A (CAS 649765-80-0)
- Dihydralazine EP Impurity C (CAS 86-54-4)
- Dihydralazine Mesylate - API Standards (CAS 69467-96-5)
- Dihydralazine Hydrochloride EP Impurity C (CAS 304-20-1)
- Dihydralazine EP Impurity A HCl (CAS 649765-80-0 (free base))
Recommended Standards
- Quinolin-8-yl (4-bromophenyl)carbamate (CAS 99541-03-4)
- Roxadustat Impurity 142 (CAS CATO-C4X-2213142)
- N-(4-Bromophenyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide (CAS 62033-67-4)
- Perampanel Impurity 22 (CAS CATO-C4X-243022)
- Meloxicam impurity 13 (CAS CATO-C4X-169013)
- Vitamin B1 Impurity 14 (CAS CATO-C4X-187314)
- Inosine impurity 4 (CAS 126222-04-6)
- 6-Bromoindazole-4-carbonitrile (CAS 898747-00-7)
- (1E,2E)-1,2-Bis(pyridin-4-ylmethylene)hydrazine (CAS 197644-96-5)
- 2-Isopropyl-5-oxohexanoic acid (CAS 2543-54-6)
- 2,2,2-Trifluoro-4’-methoxyacetophenone (CAS 711-38-6)
- 2-(Hexadecylthio)benzofuran (CAS 197565-73-4)
- 3-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 50844-60-5)
- Peptide 441 (CAS CATO-CPTD788441)
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