Linaclotide impurity 36 CAS CATO-C4X-210636
| CAS No. | CATO-C4X-210636 |
| Molecular Formula | C59H79N15O21S6 |
| Molecular Weight | 1526.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Linaclotide impurity 36.
As a process- or degradation-related impurity, Linaclotide impurity 36 (CAS CATO-C4X-210636, C59H79N15O21S6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Linaclotide impurity 36 (C59H79N15O21S6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 28.0, corresponding to approximately 28 ring(s) or double-bond equivalent(s). With a molecular weight of 1526.73 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C59H79N15O21S6 |
| Molecular Weight | 1526.73 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 15 |
| Sulfur Atoms | 6 |
Related Linaclotide Standards
- Linaclotide Impurity 18 (CAS CATO-C4X-210618)
- Linaclotide Impurity 19 (CAS CATO-C4X-210619)
- Linaclotide Impurity 20 (CAS CATO-C4X-210620)
- Linaclotide Impurity 21 (CAS CATO-C4X-210621)
- Linaclotide Impurity 22 (CAS CATO-C4X-210622)
- Linaclotide Impurity 23 (CAS CATO-C4X-210623)
- Linaclotide Impurity 24 (CAS CATO-C4X-210624)
- Linaclotide Impurity 25 (CAS CATO-C4X-210625)
Recommended Standards
- Linaclotide Impurity 30 (CAS CATO-C4X-210630)
- D-Cys5-Linaclotide (CAS CATO-C4X-210611)
- Linaclotide Impurity 29 (CAS CATO-C4X-210629)
- Linaclotide Impurity 46 (CAS CATO-C4X-210646)
- Sugammadex Impurity Org198958-2 (CAS 2412953-11-6)
- Sarpogrelate Impurity 19 (CAS CATO-C4X-291319)
- Finerenone Impurity 48 (CAS CATO-C4X-288048)
- 4-Bromo-5-cyclopropoxy-N,N-dimethylpyridin-3-amine (CAS 1243363-45-2)
- 4-(chloromethyl)-2-(2,4-dimethoxyphenyl)-1,3-thiazole (CAS 900640-86-0)
- tert-Butyl 6-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate (CAS 1956385-79-7)
- 5-Oxo-7-(trimethylsilyl)-6-heptynoic Acid 1-Methylethyl Ester (CAS 1251537-12-8)
- Formylproline (CAS 67985-73-3)
- 3-Chloro-6-(4-piperidin-1-ylphenyl)pyridazine (CAS 1105194-54-4)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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