Gadobutrol Impurity 186 CAS CATO-C4X-2120186
| CAS No. | CATO-C4X-2120186 |
| Molecular Formula | C15H28N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Gadobutrol Impurity 186 (CAS CATO-C4X-2120186), a pharmacopoeial impurity reference standard (molecular formula C15H28N4O6C2H2O4, MW 450.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Gadobutrol Impurity 186 (C15H28N4O6C2H2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gadobutrol Impurity 186 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H28N4O6 C2H2O4 |
| Molecular Weight | 450.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Gadobutrol Standards
- Gadobutrol Impurity 112 (CAS 1003-83-4)
- Gadobutrol Impurity 12 4HCl (CAS 10045-25-7)
- Gadobutrol Impurity 79 (CAS 105855-71-8)
- Gadobutrol Impurity 115 (CAS 112-24-3)
- Gadobutrol EP Impurity C (Gadoteridol USP Related Compound B) (CAS 112188-16-6)
- Gadobutrol Impurity N5 (CAS 112193-75-6)
- Gadobutrol Impurity 104 4HCl (CAS 112193-75-6（free base）)
- Gadobutrol Impurity 37 (Cyclen Disulfate) (CAS 112193-77-8)
Recommended Standards
- Letermovir Impurity 79 (CAS CATO-C4X-291579)
- Cabergoline EP Impurity B (CAS 166533-36-4)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
- methyl 5-[4-(difluoromethoxy)phenyl]-1h-pyrazole-3-carboxylate (CAS 1092774-03-2)
- 2-Amino-4,5-dihydroxybenzoic Acid (CAS 114874-99-6)
- 3-(1H-benzo[d]imidazol-2-yl)-8-ethoxy-2H-chromen-2-one (CAS 314048-15-2)
- [(5-Fluoro-1H-benzimidazol-2-yl)methoxy]-acetic acid (CAS 915920-11-5)
- 3-[(3-chloro-4-methylphenyl)amino]propanenitrile (CAS 565166-65-6)
- S-(cyclopropylmethyl) ethanethioate (CAS 1269292-10-5)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com