Fluralaner impurity 45 CAS CATO-C4X-218045
| CAS No. | CATO-C4X-218045 |
| Molecular Formula | C10H3ClF6O2 |
| Molecular Weight | 304.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fluralaner impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Fluralaner impurity 45 (CAS CATO-C4X-218045) is a certified pharmaceutical impurity reference standard with the molecular formula C10H3ClF6O2 and a molecular weight of 304.57 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Fluralaner impurity 45 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 304.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H3ClF6O2 |
| Molecular Weight | 304.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Fluralaner Standards
- Fluralaner Impurity 19 (CAS CATO-C4X-218019)
- Fluralaner impurity 44 (CAS 1655515-91-5)
- Fluralaner Impurity 20 (CAS CATO-C4X-218020)
- Fluralaner Impurity 18 (CAS CATO-C4X-218018)
- Fluralaner Impurity 48 (CAS CATO-C4X-218048)
- Fluralaner Impurity 49 (CAS CATO-C4X-218049)
- Fluralaner impurity 40 (CAS CATO-C4X-218040)
- Fluralaner Impurity 4 (mix TBC as stabilizer) (CAS 864725-22-4)
Recommended Standards
- tert-butyldimethylsilyl 2-[(tert-butyldimethylsilyl)oxy]acetate (CAS 67226-76-0)
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- 2-(4-Bromo-2-chlorophenoxy)-N-cyclopropylacetamide (CAS 797000-22-7)
- 1-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2773311-26-3)
- Lusutrombopag Impurity 41 (CAS CATO-C4X-208441)
- Canagliflozin Impurity 106 (CAS CATO-C4X-1123106)
- Rivaroxaban EP Impurity A (CAS 865479-71-6)
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- 2-((6-Acetamidopyridazin-3-yl)thio)-N-(thiophen-2-ylmethyl)acetamide (CAS 1021060-65-0)
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- 7-Methyl-1,6,7,8-tetrahydroimidazo[4,5-e]isoindole (CAS 159724-77-3)
- 6-Chloro-N,N-dimethyl-2-(methylsulfinyl)pyrimidin-4-amine (CAS 1353945-21-7)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
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