Beraprost Impurity 18 CAS CATO-C4X-218418
| CAS No. | CATO-C4X-218418 |
| Molecular Formula | C16H17BrO5 |
| Molecular Weight | 369.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Beraprost Impurity 18 (C16H17BrO5) contains a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Beraprost Impurity 18 (CAS CATO-C4X-218418) is a certified pharmaceutical impurity reference standard with the molecular formula C16H17BrO5 and a molecular weight of 369.21 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H17BrO5 |
| Molecular Weight | 369.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Beraprost Standards
- Beraprost Impurity 20 (CAS CATO-C4X-218420)
- Beraprost Impurity 22 (CAS 88277-22-9)
- Beraprost Impurity 4(discontinue,see C4X-218413) (CAS CATO-C4X-21844)
- Beraprost Impurity 32 (CAS CATO-C4X-218432)
- Beraprost Impurity 5 (Mixture of Diastereomers) (CAS CATO-C4X-21845)
- Beraprost Impurity 24 (CAS CATO-C4X-218424)
- Beraprost Impurity 7 (CAS CATO-C4X-21847)
- Beraprost Impurity 30 (CAS CATO-C4X-218430)
Recommended Standards
- N'-(4-bromobenzoyl)-1-naphthohydrazide (CAS 84282-40-6)
- Phenyl (2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (CAS 1914078-87-7)
- N'-(3-bromobenzoyl)-2-naphthohydrazide (CAS 84282-41-7)
- PD168393 (CAS 194423-15-9)
- Belinostat Impurity 5 (CAS CATO-C4X-34905)
- Rosuvastatin Impurity 235 (CAS CATO-C4X-1169235)
- Ertugliflozin Impurity 48 (CAS CATO-C4X-301148)
- 2-[(2-chlorophenyl)formamido]-4-(methylsulfanyl)butanoic acid (CAS 65054-72-0)
- 4-Hydroxy-5-methylisophthalic acid (CAS 4365-31-5)
- 5-Bromo-1-(4-fluorobenzyl)pyridin-2(1h)-one (CAS 1276517-14-6)
- 2-((1S)-1-amino-2-hydroxyethyl)pyridin-3-ol (CAS 1212933-17-9)
- Methyl 4-(4-ethylphenyl)-4-oxobutanoate (CAS 56705-44-3)
- tert-Butyl 4-methyl-3-oxo-2-phenylpiperazine-1-carboxylate (CAS 1421762-88-0)
- Tirzepatide (CAS 2023788-19-2)
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