Lumateperone Impurity 12 CAS CATO-C4X-220112
| CAS No. | CATO-C4X-220112 |
| Molecular Formula | C17H23N3O2 |
| Molecular Weight | 301.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lumateperone Impurity 12.
CATO supplies Lumateperone Impurity 12 (CAS CATO-C4X-220112), a pharmacopoeial impurity reference standard (molecular formula C17H23N3O2, MW 301.38 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Lumateperone Impurity 12 (C17H23N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H23N3O2 |
| Molecular Weight | 301.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Lumateperone Standards
- Lumateperone Impurity 13（and enantiomer） (CAS 313544-77-3)
- Lumateperone Impurity 80 (CAS CATO-C4X-220180)
- Lumateperone Impurity 69 (CAS CATO-C4X-220169)
- Lumateperone Impurity 79 (CAS CATO-C4X-220179)
- Lumateperone Impurity N3 (CAS 313369-16-3)
- Lumateperone Impurity N6（and enantiomer） (CAS 313544-32-0)
- Lumateperone Impurity 66 (CAS CATO-C4X-220166)
- Lumateperone impurity 59 (CAS CATO-C4X-220159)
Recommended Standards
- Olodaterol impurity 36 (CAS CATO-C4X-194336)
- Glycopyrrolate Impurity 6 (CAS 1202407-99-5)
- Atropine impurity 65 (CAS CATO-C4X-148965)
- Bilastine impurity 137 (CAS CATO-C4X-2253137)
- Fosfomycin Impurity 81 (CAS 734473-80-4)
- Venlafaxine Impurity 25 (CAS CATO-C4X-143425)
- Ganaxolone Impurity 1 (CAS 1264737-31-6)
- Isoprenaline Impurity 7 (CAS CATO-C4X-27757)
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- tert-butyl 4-aminooxane-4-carboxylate (CAS 1557187-54-8)
- Methyl 6-bromo-2-(trifluoromethyl)nicotinate (CAS 1227581-53-4)
- 2-(piperidin-4-yl)-4-(pyridin-3-yl)pyrimidine dihydrochloride (CAS 2060037-89-8)
- 3-[(thiophen-2-ylsulfanyl)methyl]-1-benzofuran-2-carboxylic acid (CAS 1039891-26-3)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com