Lumateperone Impurity 22 CAS CATO-C4X-220122
| CAS No. | CATO-C4X-220122 |
| Molecular Formula | C11H13BrN2 |
| Molecular Weight | 253.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lumateperone Impurity 22 (CAS CATO-C4X-220122, C11H13BrN2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lumateperone Impurity 22 (C11H13BrN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13BrN2 |
| Molecular Weight | 253.14 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Lumateperone Standards
- Lumateperone Impurity 16 (CAS 1059630-17-9)
- Lumateperone Impurity 23 (CAS CATO-C4X-220123)
- Lumateperone impurity 25 (CAS CATO-C4X-220125)
- Lumateperone Impurity 38 (CAS CATO-C4X-220138)
- Lumateperone Impurity 15 (CAS CATO-C4X-22015)
- Lumateperone impurity 61 (CAS CATO-C4X-220161)
- Lumateperone impurity 58 (CAS CATO-C4X-220158)
- Lumateperone Impurity 45 (CAS CATO-C4X-220145)
Recommended Standards
- N,N-diallyl-5-bromopyridin-2-amine (CAS 309977-78-4)
- 1-(4-Chlorophenyl)propane-2-sulfonyl chloride (CAS 1017338-18-9)
- Ethyl 4,4,4,4',4',4'-hexafluoro-DL-valinate (CAS 78185-92-9)
- 1-Nitro-4-(2,2,3,3-tetrafluoropropoxy)benzene (CAS 109230-72-0)
- Tenofovir disoproxil impurity 123 (CAS 1962114-92-6)
- Theophylline Impurity 14 (CAS CATO-C4X-182314)
- Alfacalcidol Impurity 7 (CAS CATO-C4X-13937)
- 6-Methyl-5-(piperidin-2-yl)pyridin-2-amine (CAS 1270501-37-5)
- n-Cyclopropyl-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 923122-00-3)
- 2-(3-(1,1,2,2-Tetrafluoroethyl)-1H-pyrazol-5-yl)phenol (CAS 378754-97-3)
- Fmoc-Leu-Ser-OH (CAS 2171235-49-5)
- Hydrochlorothiazide Impurity 22 (CAS 63779-86-2)
- 1-(2-Chlorophenyl)-2,3-butadien-1-one (CAS 196952-95-1)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
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