Semaglutide Impurity 158 (x TFA Salt) CAS CATO-C4X-2226158
| CAS No. | CATO-C4X-2226158 |
| Molecular Formula | C187H291N45O60 |
| Molecular Weight | 4129.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Semaglutide Impurity 158 (x TFA Salt) (C187H291N45O60) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158), a pharmacopoeial impurity reference standard (molecular formula C187H291N45O60, MW 4129.64 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Semaglutide Impurity 158 (x TFA Salt) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C187H291N45O60 |
| Molecular Weight | 4129.64 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 65.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 45 |
Related Semaglutide Standards
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
- Semaglutide (CAS 910463-68-2（free base）)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
- Glu17-Semaglutide (CAS CATO-C4X-2226209)
Recommended Standards
- Teriparatide-d10 (CAS 52232-67-4 (Unlabeled))
- Teriparatide-d10 TFA Salt (CAS CATO-C4X-21854)
- (Pyr3)-Amyloid β-Protein (3-40) trifluoroacetate salt (CAS 161818-04-8)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
- Apremilast impurity 93 (CAS 2733027-41-1)
- Mivacurium chloride Impurity 49 (CAS CATO-C4X-137549)
- Rimegepant Impurity 53 DiHCl (CAS CATO-C4X-248753)
- 4,6-Dimethoxypyrimidin-5-methylamine (CAS 1118786-90-5)
- 4-((3-Methoxyphenyl)amino)tetrahydro-2H-thiopyran-4-carboxylic acid (CAS 1281266-49-6)
- N-((4-chlorobenzoyl)oxy)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 860787-53-7)
- CM 4620 (CAS 1713240-67-5)
- 3-Methylcyclopentanol, mixture of isomers (CAS 18729-48-1)
- CGS 19755 (CAS 110347-85-8)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com