Difenidol Impurity 12 CAS CATO-C4X-222712
| CAS No. | CATO-C4X-222712 |
| Molecular Formula | C21H25N |
| Molecular Weight | 291.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Difenidol Impurity 12.
CATO supplies Difenidol Impurity 12 (CAS CATO-C4X-222712), a pharmacopoeial impurity reference standard (molecular formula C21H25N, MW 291.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Difenidol Impurity 12 (C21H25N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H25N |
| Molecular Weight | 291.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Difenidol Standards
- Difenidol - API Standards (CAS 972-02-1)
- Difenidol Impurity 3 (CAS 63645-18-1)
- Difenidol Impurity 1 (CAS 40220-79-9)
- Difenidol Impurity 10 (CAS 5180-33-6)
- Difenidol Impurity 11 (CAS 778-66-5)
- Difenidol Impurity 2 HCl (CAS CATO-C4X-22272)
- Difenidol Impurity 4 HCl (CAS 55701-20-7)
- Difenidol Impurity 5 HCl (CAS CATO-C4X-22275)
Recommended Standards
- Venlafaxine Impurity 58 (CAS 1000377-27-4)
- Penbutolol (CAS 38363-40-5)
- Terbinafine Impurity 52 (CAS 2416665-26-2)
- rac Penbutolol (CAS 36507-48-9)
- Olaparib Impurity N14 (CAS 1983186-05-5)
- Aciclovir Impurity 30 (CAS 59277-91-7)
- Pethidine impurity 11 (CAS CATO-C4X-223211)
- Xanomeline Impurity 16 (CAS CATO-C4X-330116)
- 2,4-Difluoro-n'-hydroxybenzene-1-carboximidamide (CAS 883022-90-0)
- 2-(Pyrrolidin-3-yl)-2H-1,2,3-triazole (CAS 1186300-55-9)
- 3-Methoxybicyclo[1.1.1]pentan-1-amine (CAS 1934969-81-9)
- 2-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4-methylaniline (CAS 1036600-97-1)
- Tert-butyl 7'-bromo-4'-oxospiro[azetidine-3,2'-chromane]-1-carboxylate (CAS 1456724-57-4)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com