Pirfenidone Impurity 8 CAS CATO-C4X-22298
| CAS No. | CATO-C4X-22298 |
| Molecular Formula | C12H11NO2 |
| Molecular Weight | 201.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Pirfenidone Impurity 8 (CAS CATO-C4X-22298), a pharmacopoeial impurity reference standard (molecular formula C12H11NO2, MW 201.22 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Pirfenidone Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11NO2 |
| Molecular Weight | 201.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Pirfenidone Standards
- Pirfenidone Impurity 10 (CAS CATO-C4X-222910)
- Pirfenidone Impurity 12 (CAS 887406-49-7)
- Pirfenidone Impurity 21 (CAS 887406-53-3)
- Pirfenidone Impurity 23 (CAS 851518-71-3)
- Pirfenidone Impurity 45 (CAS CATO-C4X-222945)
- Pirfenidone Impurity 48 (CAS CATO-C4X-222948)
- Pirfenidone-d5 (5-Methyl-N-Phenyl-2-1H-Pyridone-d5) (CAS 1020719-62-3)
- Pirfenidone D3 (CAS 1093951-85-9)
Recommended Standards
- Finerenone Impurity 166 (CAS CATO-C4X-2880166)
- Finerenone Impurity 171 (CAS CATO-C4X-2880171)
- Mirogabalin Impurity 129 (CAS CATO-C4X-2924129)
- Ivacaftor Impurity 12 (CAS CATO-C4X-296412)
- Norepinephrine Impurity 108 (CAS CATO-C4X-1514108)
- Rocuronium Impurity 32 (CAS CATO-C4X-124232)
- Tolvaptan Impurity 91 (CAS CATO-C4X-195591)
- Tert-butyl (2S,4R)-2-(bromomethyl)-4-hydroxypyrrolidine-1-carboxylate (CAS 2306245-49-6)
- 3-Chloro-2-methoxypyridine hydrate (CAS 1881293-92-0)
- (3-Chloro-4-propoxyphenyl)methanamine (CAS 776997-51-4)
- tert-Butyl 2-oxo-5,6-dihydropyridine-1(2H)-carboxylate (CAS 128372-89-4)
- N-Allyl-5-(4-chlorophenyl)-2-methylfuran-3-carboxamide (CAS 941238-50-2)
- ditert-butyl 6-methyl-2,5,8-triazaspiro[3.5]nonane-2,8-dicarboxylate (CAS 1639963-77-1)
- Neuropeptide K, porcine (CAS 106441-70-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com