Avatrombopag Impurity 66 CAS CATO-C4X-223466
| CAS No. | CATO-C4X-223466 |
| Molecular Formula | C8H13NO2 |
| Molecular Weight | 155.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 155.19 g/mol gives Avatrombopag Impurity 66 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Avatrombopag Impurity 66 (CAS CATO-C4X-223466) is a certified pharmaceutical impurity reference standard with the molecular formula C8H13NO2 and a molecular weight of 155.19 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Avatrombopag Impurity 66 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 155.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avatrombopag Impurity 66 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13NO2 |
| Molecular Weight | 155.19 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 1 |
Related Avatrombopag Standards
- Avatrombopag Impurity 65 (CAS CATO-C4X-223465)
- Avatrombopag Impurity 31 (CAS 1126-09-6)
- Avatrombopag Impurity 36 (CAS 34730-20-6)
- Avatrombopag Impurity 37 (CAS 17766-28-8)
- Avatrombopag Impurity 40 (CAS 54127-63-8)
- Avatrombopag Impurity 54 (CAS 28989-50-6)
- Avatrombopag Impurity 92 (CAS 160114-74-9)
- Avatrombopag Impurity 85 (CAS 677762-31-1)
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