Baricitinib Impurity 108 CAS CATO-C4X-2260108

Purity 95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2260108
Molecular FormulaC27H38N8O2Si2
Molecular Weight562.81 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Baricitinib Impurity 108 CAS CATO-C4X-2260108 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO supplies Baricitinib Impurity 108 (CAS CATO-C4X-2260108), a pharmacopoeial impurity reference standard (molecular formula C27H38N8O2Si2, MW 562.81 g/mol) used for the identification and quantification of trace impurities in APIs.

Baricitinib Impurity 108 (C27H38N8O2Si2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO manufactures Baricitinib Impurity 108 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC27H38N8O2Si2
Molecular Weight562.81 g/mol
AppearancePale yellow to yellow crystalline powder
Purity95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms8

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