CMC2026 Impurity 3 CAS CATO-C4X-22663
| CAS No. | CATO-C4X-22663 |
| Molecular Formula | C22H23ClF4N2O4S |
| Molecular Weight | 522.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including CMC2026 Impurity 3.
CMC2026 Impurity 3 (CAS CATO-C4X-22663) is a certified pharmaceutical impurity reference standard with the molecular formula C22H23ClF4N2O4S and a molecular weight of 522.94 g/mol.
CMC2026 Impurity 3 (C22H23ClF4N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), CMC2026 Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H23ClF4N2O4S |
| Molecular Weight | 522.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- 7-(Chlorodifluoromethyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine (CAS 439097-22-0)
- Penfluridol Impurity 13 (CAS CATO-C4X-353813)
- Cefuroxime Impurity 71 (CAS CATO-C4X-124571)
- Flomoxef Impurity 28 (CAS CATO-C4X-138228)
- Ubenimex Impurity 10 HCl (CAS CATO-C4X-182510)
- Penehyclidine impurity 31 (CAS CATO-C4X-130431)
- Pidotimod Impurity N7 (CAS 21282-16-6)
- 1-(2-Ethoxyethyl)-1,4-diazepane (CAS 1094643-96-5)
- 2-((Ethyl(methyl)(oxo)-lambda6-sulfanylidene)amino)acetonitrile (CAS 1934871-40-5)
- Tert-butyl n-[(2r)-2-(4-fluorophenyl)-2-hydroxyethyl]carbamate (CAS 1311320-28-1)
- (1S,4S)-4-(5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexan-1-ol (CAS 2227199-18-8)
- N-Boc-3-(aminomethyl)cyclopentan-1-ol, 97% (CAS 1007306-65-1)
- N-(2,4,5-Trimethoxybenzyl)cyclohexanamine hydrobromide (CAS 1609407-25-1)
- β-Asp9-Tirzepatide (CAS CATO-CPTD788931)
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