Cyclophosphamide impurity 28 CAS CATO-C4X-230628
| CAS No. | CATO-C4X-230628 |
| Molecular Formula | C13H30ClN2O9P |
| Molecular Weight | 424.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Cyclophosphamide impurity 28 (CAS CATO-C4X-230628), a pharmacopoeial impurity reference standard (molecular formula C13H30ClN2O9P, MW 424.81 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cyclophosphamide impurity 28 (C13H30ClN2O9P) is characterized by an amide group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H30ClN2O9P |
| Molecular Weight | 424.81 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -0.5 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cyclophosphamide Standards
- Cyclophosphamide Impurity 46 (CAS CATO-C4X-230646)
- Cyclophosphamide Impurity 2 (CAS CATO-C4X-23062)
- Cyclophosphamide impurity 29 (CAS CATO-C4X-230629)
- Cyclophosphamide Impurity 48 (CAS CATO-C4X-230648)
- Cyclophosphamide impurity 39 (CAS CATO-C4X-230639)
- Cyclophosphamide impurity 41 (CAS CATO-C4X-230641)
- Cyclophosphamide impurity 30 (CAS 2924754-60-7)
- Cyclophosphamide impurity 33 (CAS CATO-C4X-230633)
Recommended Standards
- Methyl 3-(2-chloro-6-fluorophenyl)-5-[(1Z)-1-(dimethylamino)-4-ethoxy-3,4-dioxobut-1-en-2-yl]-1,2-oxazole-4-carboxylate (CAS 1164473-36-2)
- (5-((2-Chlorobenzyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl propionate (CAS 955962-84-2)
- N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-5-methyl-3-phenylisoxazole-4-carboxamide (CAS 338409-34-0)
- (5-((4-Chlorobenzyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl propionate (CAS 955976-43-9)
- Acetylcysteine impurity 66 (CAS 16708-09-1)
- Regorafenib Impurity 38 (CAS CATO-C4X-104738)
- Acarbose EP Impurity A (CAS 1013621-79-8)
- 6-Amino-3-fluoro-2-hydroxybenzonitrile (CAS 2090014-06-3)
- Methyl 2-hydroxybutanoate (CAS 29674-47-3)
- Chloropentamethyldisilane (CAS 1560-28-7)
- 2-Hydroxy-3-phenyl-6-(trifluoromethyl)pyridine (CAS 1214353-50-0)
- (2-((4-Bromobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopropyl)methanone (CAS 851800-36-7)
- 5-((Methylamino)methyl)-2-selenoxo-2,3-dihydropyrimidin-4(1H)-one (CAS 114482-38-1)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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