Pefloxacin Impurity 8 CAS CATO-C4X-23338
| CAS No. | CATO-C4X-23338 |
| Molecular Formula | C14H14Cl2FNO3 |
| Molecular Weight | 334.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pefloxacin Impurity 8.
CATO supplies Pefloxacin Impurity 8 (CAS CATO-C4X-23338), a pharmacopoeial impurity reference standard (molecular formula C14H14Cl2FNO3, MW 334.17 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Pefloxacin Impurity 8 (C14H14Cl2FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14Cl2FNO3 |
| Molecular Weight | 334.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Pefloxacin Standards
- Pefloxacin Impurity 7 (CAS CATO-C4X-23337)
- Pefloxacin-D5 (CAS 1228182-51-1)
- Pefloxacin Mesilate Dihydrate EP Impurity D (CAS 85145-21-7)
- Pefloxacin Mesilate Dihydrate EP Impurity B (CAS 70458-73-0)
- Pefloxacin Impurity 1 (CAS 81530-83-8)
- Pefloxacin Impurity 9 (CAS 125292-94-6)
- Pefloxacin Mesilate Dihydrate EP Impurity G (CAS 70458-94-5)
- Pefloxacin Impurity 2 (CAS CATO-C4X-23332)
Recommended Standards
- 1-(1,1-Dimethylethyl) 4-(4-boronobenzoyl)-1-piperazinecarboxylate (CAS 1150114-76-3)
- Crisaborole lmpurity 84 (CAS CATO-C4X-202184)
- (3-(4-(Tert-butoxycarbonyl)piperazine-1-carbonyl)phenyl)boronic acid (CAS 1218790-82-9)
- Norfloxacin Impurity 67 (CAS CATO-C4X-146867)
- N-Nitroso Acarbose impurity 12 (CAS CATO-C4X-117312)
- Tenofovir alafenamide Impurity 96 (CAS CATO-C4X-179796)
- Pitolisant impurity 35 (CAS CATO-C4X-252035)
- 6-Bromoquinoline-2-thiol (CAS 1330754-36-3)
- (2S,4S)-1-ISOPROPYL-4-METHOXY-PROLINE (CAS 1820571-30-9)
- Methyl 1-amino-2,3-dihydro-1h-indene-1-carboxylate (CAS 90104-36-2)
- 4-Methyl-1,3-thiazolidine (CAS 33174-83-3)
- tert-Butyl (4-oxopiperidin-3-yl)carbamate (CAS 1506277-10-6)
- (E)-2-((2-chloro-5-nitrobenzylidene)amino)isoindoline-1,3-dione (CAS 1610550-64-5)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com