Piperaquine Impurity 3 CAS CATO-C4X-23373
| CAS No. | CATO-C4X-23373 |
| Molecular Formula | C28H31Cl2N5 |
| Molecular Weight | 508.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Piperaquine Impurity 3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 508.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Piperaquine Impurity 3 (CAS CATO-C4X-23373) is a certified pharmaceutical impurity reference standard with the molecular formula C28H31Cl2N5 and a molecular weight of 508.49 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Piperaquine Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H31Cl2N5 |
| Molecular Weight | 508.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Piperaquine Standards
- Piperaquine Impurity 10 (CAS CATO-C4X-233710)
- Piperaquine Impurity 5 (CAS CATO-C4X-23375)
- Piperaquine Base (CAS 4085-31-8)
- Piperaquine Phosphate (CAS 85547-56-4)
- Piperaquine Tetraphosphate (CAS 911061-10-4)
- Piperaquine Impurity 8 (CAS 918879-09-1)
- Piperaquine D6 (CAS 1261394-71-1)
- Piperaquine Impurity 9 (CAS 1233345-93-1)
Recommended Standards
- Methyl 2-3-6-tri-O-benzyl-4-deoxy-4-fluoro-α-D-glucopyranoside (CAS 84065-98-5)
- 4-((4-(Hexylcarbamoyl)-2-(naphthalen-1-yl)oxazol-5-yl)methyl)phenyl dihydrogen phosphate (CAS 1003580-86-6)
- (Z)-{2,2,2-trifluoro-1-[1-(4-fluorophenyl)-5-(4-methanesulfonylphenyl)-2-methyl-1H-pyrrol-3-yl]ethylidene}amino cyclopropanecarboxylate (CAS 860788-03-0)
- 1-((2R)-1-[(11bR)-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yloxy]propan-2-yl}-3-phenylurea (CAS 1198080-53-3)
- N-Nitroso Ziprasidone EP Impurity A (CAS CATO-C4X-124054)
- Iguratimod Impurity 86 (CAS CATO-C4X-182686)
- Ivabradine impurity 82 (CAS 73344-75-9（free base))
- Dronedarone-d6 HCl (CAS 1329809-23-5)
- (1s)-2-Bromo-1-(4-methanesulfonylphenyl)ethan-1-ol (CAS 1212121-62-4)
- (R)-Methyl 2,2-dimethylmorpholine-3-carboxylate hydrochloride (CAS 1416445-03-8)
- Piperidine-3,3-dicarbonitrile hydrochloride (CAS 1374653-23-2)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-6-[(E)-2-(4-methylphenyl)ethenyl]-4-[(Z)-2-(4-methylphenyl)ethenyl]pyridine-3-carbonitrile (CAS 303985-42-4)
- 2-(4-tert-Butylphenyl)-5-methyl-1,3,4-oxadiazole (CAS 477862-37-6)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com