Pilocarpine Impurity 18 CAS CATO-C4X-240118
| CAS No. | CATO-C4X-240118 |
| Molecular Formula | C11H16N2O3 |
| Molecular Weight | 224.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Pilocarpine Impurity 18 (CAS CATO-C4X-240118), a pharmacopoeial impurity reference standard (molecular formula C11H16N2O3, MW 224.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Pilocarpine Impurity 18 (C11H16N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O3 |
| Molecular Weight | 224.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Pilocarpine Standards
- Pilocarpine Impurity 22 (CAS CATO-C4X-240122)
- Pilocarpine Impurity 4 (CAS CATO-C4X-24014)
- Pilocarpine Hydrochloride EP Impurity B (CAS 28406-15-7)
- Pilocarpine Hydrochloride EP Impurity C (CAS 34350-99-7)
- Pilocarpine Impurity 20 (CAS CATO-C4X-240120)
- Pilocarpine (CAS 92-13-7)
- Pilocarpine Impurity 11 (CAS CATO-C4X-240111)
- Pilocarpine EP Impurity B Sodium Salt (CAS 92598-79-3)
Recommended Standards
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- N-Nitroso Verapamil Impurity-1 (CAS CATO-C4X-177840)
- Benzydamine EP Impurity C (CAS 2215-63-6)
- Ozagrel Impurity 30 (CAS CATO-C4X-197130)
- Iopromide Impurity 18 (CAS CATO-C4X-183218)
- Florfenicol Impurity 70 (CAS 126428-97-5)
- 2-(2,5-Dioxopyrrolidin-1-yl)acetonitrile (CAS 61516-81-2)
- 7-Bromo-3,3-dimethyl-2,3-dihydropyrazolo[5,1-b]oxazole (CAS 2676863-02-6)
- 6,6-difluoro-2-oxabicyclo[3.1.0]hexane-1-carbonitrile (CAS 1955557-96-6)
- 2-((3,5-Dimethylcyclohexyl)amino)ethan-1-ol (CAS 1343193-91-8)
- Evocalcet Impurity 35 DiHCl Isopropylate (CAS 870858-86-9(HCl))
- 1H-Pyrazole, 1-[(2-chloro-6-fluorophenyl)methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- (CAS 1604036-86-3)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
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