Opicapone Impurity 49 CAS CATO-C4X-240449
| CAS No. | CATO-C4X-240449 |
| Molecular Formula | C15H11ClN4O6 |
| Molecular Weight | 378.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Opicapone Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Opicapone Impurity 49 (CAS CATO-C4X-240449, C15H11ClN4O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Opicapone Impurity 49 (C15H11ClN4O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H11ClN4O6 |
| Molecular Weight | 378.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Opicapone Standards
- Opicapone Impurity 51 (CAS CATO-C4X-240451)
- Opicapone Impurity 55 (CAS CATO-C4X-240455)
- Opicapone impurity 30 (CAS CATO-C4X-240430)
- Opicapone impurity 20 (CAS 2824922-36-1)
- Opicapone Impurity 56 (CAS CATO-C4X-240456)
- Opicapone Impurity 10 (CAS CATO-C4X-240410)
- Opicapone Impurity N2 (CAS 952091-17-7)
- Opicapone Impurity 9 (CAS CATO-C4X-24049)
Recommended Standards
- 5-Bromo-2-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one (CAS 2409579-63-9)
- (Z)-12-Heptacosene (CAS 54863-74-0)
- N-(3-Chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetamide (CAS 1632286-05-5)
- 6-(3-Chlorobenzoyl)-2-phenyl-5-(trifluoromethyl)pyridazin-3(2H)-one (CAS 478043-61-7)
- Clofazimine Impurity 14 (CAS CATO-C4X-207114)
- Azelastine Impurity 49 (CAS CATO-C4X-139649)
- Cenobamate Impurity 20 (CAS CATO-C4X-241620)
- Methyl 1-(pyridin-3-yl)piperidine-4-carboxylate (CAS 1823499-87-1)
- N1-(2-(Cyclohex-1-en-1-yl)ethyl)-N2-(2-(furan-3-yl)ethyl)oxalamide (CAS 1706220-69-0)
- 2-methyloxolane-3-sulfonamide (CAS 1423027-27-3)
- (R)-3-((tert-Butoxycarbonyl)amino)-2-(hydroxymethyl)propanoic acid (CAS 1190870-93-9)
- 3-methyl-3-(2-methylpropyl)piperazin-2-one (CAS 78551-70-9)
- (Butan-2-yl)(3-phenylbutyl)amine hydrochloride (CAS 1240572-57-9)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
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