Opicapone Impurity 77 CAS CATO-C4X-240477

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-240477
Molecular FormulaC24H19Cl2N5O12
Molecular Weight640.34 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Opicapone Impurity 77 CAS CATO-C4X-240477 chemical structure

Description

CATO supplies Opicapone Impurity 77 (CAS CATO-C4X-240477), a pharmacopoeial impurity reference standard (molecular formula C24H19Cl2N5O12, MW 640.34 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Opicapone Impurity 77 (C24H19Cl2N5O12) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Opicapone Impurity 77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC24H19Cl2N5O12
Molecular Weight640.34 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms5

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