Upadacitinib Impurity 152 CAS CATO-C4X-2405152
| CAS No. | CATO-C4X-2405152 |
| Molecular Formula | C18H23NO4 |
| Molecular Weight | 317.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Upadacitinib Impurity 152 (CAS CATO-C4X-2405152), a pharmacopoeial impurity reference standard (molecular formula C18H23NO4, MW 317.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Upadacitinib Impurity 152 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 317.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Upadacitinib Impurity 152 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H23NO4 |
| Molecular Weight | 317.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 154 (CAS CATO-C4X-2405154)
- Upadacitinib Impurity 194 (CAS CATO-C4X-2405194)
- Upadacitinib Impurity 175 (CAS CATO-C4X-2405175)
- Upadacitinib Impurity 59 (CAS 2411540-28-6)
- Upadacitinib Impurity 100 (CAS CATO-C4X-2405100)
- Upadacitinib Impurity 179 (CAS CATO-C4X-2405179)
- Upadacitinib Impurity 136 (CAS CATO-C4X-2405136)
- Upadacitinib Impurity 114 (CAS CATO-C4X-2405114)
Recommended Standards
- Lumateperone Impurity 75 (CAS 2762307-17-3)
- Revefenacin Impurity 61 (CAS CATO-C4X-203161)
- Lifitegrast Impurity 40 (CAS CATO-C4X-240940)
- Dopamine Impurity 77 (CAS 854733-87-2)
- Fluconazole EP Impurity F (CAS 118689-07-9)
- Etrasimod impurity 8 (CAS CATO-C4X-32148)
- Bepotastine Impurity 33 (CAS CATO-C4X-183933)
- N2,N2-Bis(cyclobutylmethyl)thiazole-2,4-diamine (CAS 1707735-05-4)
- (S)-3-(3-bromophenoxy)pyrrolidine (CAS 1187927-58-7)
- n-Methyl-4-(methylamino)-n-(propan-2-yl)benzene-1-sulfonamide (CAS 1094377-22-6)
- Methyl 2-methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylate (CAS 1372540-24-3)
- Lifitegrast Impurity 41 (CAS 851785-19-8)
- Ethyl 2-((4-acetylphenyl)carbamoyl)hydrazine-1-carboxylate (CAS 706767-33-1)
- Osteogenic Growth Peptide (CAS 132996-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com