Upadacitinib Impurity 214 CAS CATO-C4X-2405214
| CAS No. | CATO-C4X-2405214 |
| Molecular Formula | C28H29N5O4S2 |
| Molecular Weight | 563.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 563.69 g/mol gives Upadacitinib Impurity 214 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Upadacitinib Impurity 214 (CAS CATO-C4X-2405214), a pharmacopoeial impurity reference standard (molecular formula C28H29N5O4S2, MW 563.69 g/mol) used for the identification and quantification of trace impurities in APIs.
Upadacitinib Impurity 214 (C28H29N5O4S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H29N5O4S2 |
| Molecular Weight | 563.69 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Upadacitinib Standards
- Upadacitinib Impurity 50 (CAS 2270173-63-0)
- Upadacitinib Impurity 69 (CAS CATO-C4X-240569)
- Upadacitinib Impurity 221 (CAS CATO-C4X-2405221)
- Upadacitinib Impurity 13 (CAS 1708997-42-5)
- Upadacitinib Impurity 209 (CAS CATO-C4X-2405209)
- Upadacitinib Impurity 51 (CAS 2270173-65-2)
- Upadacitinib Impurity 9 (CAS CATO-C4X-24059)
- Upadacitinib Impurity 93 (CAS CATO-C4X-240593)
Recommended Standards
- Dihydroergocristine EP Impurity F (CAS 25447-65-8)
- 2,2-Dimethyl-4-oxo-3,10,13,16,19,22-hexaoxa-5-azatetracosan-24-yl 4-methylbenzenesulfonate (CAS 2681390-49-6)
- tert-Butyl-7-[4-(4-fluorophenyl)-6-isopropyl-2-mesylaminopyrimidin-5-yl]-(3R,5S)-isopropylidine-(E)-6-heptenoate (CAS 371775-73-4)
- Rhodamine-6G N-Phenyl-thiosemicarbazide (CAS 885481-03-8)
- Amodiaquine Impurity 2 (CAS 79049-30-2)
- Indometacin Impurity 45 (CAS CATO-C4X-147045)
- Budesonide Impurity 80 (CAS CATO-C4X-138980)
- 2-(3-Piperidinyl)ethyl cyclopentanecarboxylatehydrochloride (CAS 1219980-89-8)
- 3,5-Dimethylpyridazine (CAS 22863-58-7)
- tert-Butyl (4-carbamoyltetrahydro-2H-pyran-4-yl)carbamate (CAS 519031-86-8)
- N-Methyl-4-methoxybenzimine (CAS 13114-23-3)
- N-(3-(2-chlorophenyl)-5-methylisoxazol-4-yl)-N-(5-methylisoxazol-3-yl)formamide (CAS 309950-35-4)
- 3-(1-(Methylsulfonyl)ethyl)aniline (CAS 773846-47-2)
- Neuropeptide Y (2-36) (human, rat) trifluoroacetate salt (CAS 123139-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com