Piperazine impurity 50 CAS CATO-C4X-242750
| CAS No. | CATO-C4X-242750 |
| Molecular Formula | C12H23N3O |
| Molecular Weight | 225.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a hydroxyl group, an ether linkage, Piperazine impurity 50 is typically white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 225.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Piperazine impurity 50 (CAS CATO-C4X-242750) is a certified pharmaceutical impurity reference standard with the molecular formula C12H23N3O and a molecular weight of 225.33 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H23N3O |
| Molecular Weight | 225.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 3 |
Related Piperazine Standards
- 1,1'-(Piperazine-1,4-diyl)bis(2-methylpropan-1-one) (CAS 18940-58-4)
- Piperazine Impurity 20 (CAS 119891-85-9)
- 1-Boc-piperazine-2-carboxylic Acid (CAS 1214196-85-6)
- 4-Boc-piperazine-2-carboxylic acid (CAS 128019-59-0)
- 3,3'-(Piperazine-1,4-diyl)dipropanoic acid (CAS 5649-49-0)
- 19984-46-4 Piperazine, 1-(1-adamantyl)- Piperazine, 1-tricyclo(3.3.1.13,7)dec-1-yl- 1-(1-Adamantyl)piperazine N-1-Adamantylpiperazine 1-(N-Piperazino)adamantane (CAS 19984-46-4)
- 2,2'-(Piperazine-1,4-diyl)bis(2-methylpropanenitrile) (CAS 408510-04-3)
- Benzyl piperazine-2-carboxylate (CAS 1624260-17-8)
Recommended Standards
- Lercanidipine Impurity 34 (CAS 28075-29-8)
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- 2-(5-Isopropyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)ethan-1-amine (CAS 1016684-85-7)
- Neticonazole Impurity 1 (CAS 2949-92-0)
- Ixazomib Impurity 74 (CAS CATO-C4X-126774)
- Pimavanserin Impurity 45 (CAS 71022-60-1)
- 2-Bromo-3-(difluoromethyl)-4-fluoropyridine (CAS 1805314-32-2)
- Methyl 1,1-difluoro-4-oxa-7-azaspiro[2.5]octane-6-carboxylate (CAS 2765271-36-9)
- Tert-butyl 4,4-difluoro-2-methylpiperidine-1-carboxylate (CAS 1445592-38-0)
- 6-Bromo-2-methyl-1H-indole (CAS 6127-19-1)
- 2-Cyano-N-(4-methylbenzyl)acetamide (CAS 64488-12-6)
- 2-(2-(5-Bromofuran-2-yl)-6-chloroimidazo[1,2-a]pyridin-3-yl)acetic acid (CAS 88623-38-5)
- Neuropeptide VF (124-131) (human) (CAS 311309-27-0)
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